MIREAE BIO MEDICINE

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Sources: Seoul National University, Harvard, Johns Hopkins, etc
Sources: ISSCA,Harvard Stem Cell Institute, MIT, Jhons Hopkins Medicine, Cleveland Clinic, Seoul National University Hospital

Liver Disease

Stem Cell Therapy for Liver Disease

Related Conditions: Liver disease, cirrhosis, fatty liver, hepatitis, liver cancer, alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), acute liver failure, chronic liver disease, hepatic encephalopathy, liver fibrosis, biliary atresia, Wilson’s disease, autoimmune hepatitis, liver abscess, portal hypertension, hepatic hemangioma, steatohepatitis, liver failure, cholecystitis.

Efficacy of Stem Cells: 줄Stem cells have the ability to regenerate damaged liver cells, reduce inflammation, and restore liver function. They are particularly effective in repairing damaged liver tissue and improving function in conditions such as chronic liver disease and cirrhosis.

Mechanism of Stem Cell Therapy for Liver Disease: Stem cells replace damaged liver cells by differentiating into new hepatocytes, facilitating tissue regeneration. They also reduce inflammation and fibrosis, improving overall liver function. Additionally, stem cells enhance blood circulation, increasing oxygen and nutrient supply to the liver.

Risks of Liver Disease

Associated Diseases and Their Risks: Liver disease can lead to conditions such as hepatitis, cirrhosis, fatty liver disease, and liver cancer. Chronic liver damage can result in severe liver dysfunction, potentially necessitating a liver transplant.

Complications of Liver Disease

Cirrhosis Progressive scarring of the liver, leading to loss of function.
Hepatic Encephalopathy Accumulation of toxins in the blood due to liver failure, affecting brain function.
Portal Hypertension Increased pressure in the portal vein due to liver damage, leading to severe complications.
Liver Cancer Chronic liver disease can lead to malignant transformation of liver cells.

Symptoms of Liver Disease

Fatigue and Weakness	• Impaired liver function affects energy metabolism, leading to persistent fatigue.
Jaundice	• The liver’s inability to process bilirubin results in yellowing of the skin and eyes.
Ascites (Fluid Retention in the Abdomen)	Fluid buildup causes abdominal swelling
Digestive Issues	Reduced ability to digest fats leads to indigestion and nausea.

Mechanism of Action

Stem cell therapy targets the root cause of liver disease by regenerating damaged hepatocytes, reducing inflammation, and reversing fibrosis. Additionally, it enhances blood flow to the liver, restoring oxygen and nutrient delivery to improve liver function.

Expected Outcomes

Patients undergoing stem cell therapy may experience relief from fatigue and jaundice, along with a reduction in fluid retention and other symptoms. Liver cell regeneration helps restore overall function, slowing or preventing progression to severe conditions such as cirrhosis. Furthermore, the risk of liver-related complications is reduced.

Results

Stem cell therapy effectively slows the progression of liver disease and enhances liver function, allowing patients to maintain a healthier lifestyle. By reducing the need for liver transplantation and preventing severe liver failure, this therapy offers long-term benefits in preserving liver function and improving overall quality of life.